TIME TO TALK ABOUT TESTOSTERONE

Misdiagnosed, ignored, underreported - but low testosterone is real, and it’s affecting millions of men every day.

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Testosterone myth

Testosterone myth

Testosterone is often mistakenly labelled as "the aggressive hormone", but there’s little scientific evidence to support this notion. In reality, testosterone plays a diverse and crucial role in the human body, with none of its functions being directly linked to anger or aggression.

Testosterone truth

Testosterone truth

Testosterone is a hormone produced in the testicles that is crucial for male health, regulating muscle mass, bone density, erections, libido, mood, cognition, energy levels, cardiovascular health, and weight management.

Maintaining healthy testosterone levels can contribute to a happier, healthier, and longer life.

Knowledge

The role of testosterone

Testosterone is crucial for men's health and plays a central role in many aspects of wellbeing. Click on each one to understand more.

The silent epidemic

Low-T, testosterone deficiency, male ageing syndrome, hypogonadism, andropause, male menopause (or "manopause"), and midlife crisis are all terms you may have come across before.



Whatever you call it, low testosterone is the hidden men's health issue that’s being overlooked by the medical community. With millions of men in the UK affected by this silent problem, we're here to drive change, be the voice of male sufferers, and provide comprehensive diagnosis and treatment support for anyone suffering the symptoms.

Low testosterone explained

Low testosterone is a medical condition where the body doesn't produce enough testosterone to maintain various essential bodily functions. When testosterone levels are low, it can lead to symptoms such as fatigue, decreased libido, erectile dysfunction, mood changes, reduced muscle mass, and increased body fat.

Classifications of low testosterone
Low testosterone (clinically known as hypogonadism) can be classified based on its origin and cause. There are two common classifications.
Primary hypogonadism

Origin: Also known as primary testicular failure, primary hypogonadism arises directly from problems within the testicles.

Common causes: The causes of primary hypogonadism can be diverse, ranging from genetic disorders like Klinefelter's Syndrome to physical issues such as undescended testicles, testicular injury, or the effects of cancer treatment. Ageing can also play a significant role in its development.

In these cases, the testicles themselves are impaired and fail to produce sufficient levels of testosterone.

hypo
What is considered a normal level of testosterone
What is considered a normal level of testosterone?

Even before birth, your testes start producing small amounts of testosterone. Levels increase throughout childhood and peak significantly during adolescence. By your early 20s, testosterone levels reach their highest point.

  • For adult men, a normal testosterone level ranges from 12 to 29 nmol/L.

  • These values do not account for age-related decline or individual symptoms, which your doctor will consider when interpreting your levels.

  • If your testosterone levels are less than 12 nmol/L and you have symptoms, you may benefit from testosterone replacement therapy (TRT) or alternative testosterone-boosting medications.

  • A 2022 study examined testosterone levels in 1,486 men aged 20 to 44. They determined normal testosterone levels for each age bracket by using the middle third of the data.

SYMPTOMS

The signs of low testosterone

If these symptoms are holding you back, Numan can help. Book a blood test to check your testosterone levels.

Erectile dysfunction

Low-T reduces nitric oxide synthesis, which is essential for the vessels carrying blood to the penis.

Decreased libido

Low-T reduces the hormonal stimulation necessary for sexual desire and arousal.

Fatigue

Low-T reduces production of red blood cells, which impairs oxygen delivery to tissues and decreases overall energy levels.

Poor sleep

Low-T reduces the production of melatonin, a hormone essential for promoting restful sleep.

Mood changes

Low-T alters the levels of serotonin and dopamine, key neurotransmitters involved in regulating emotions.

Difficulty concentrating

Low-T impacts neural circuits involved in attention and executive function, thus diminishing cognitive performance.

Loss of muscle mass

Low-T reduces protein synthesis and increases protein breakdown in muscle tissue.

Increased body fat

Low-T slows metabolism, increasing fat storage in the body.

Reduced facial and body hair growth

Low-T shortens the time hair spends growing, resulting in thinner hair.
Assess your testosterone levels

Testosterone levels & symptoms

There are many symptoms of low testosterone, with some men only exhibiting one or two, whereas numerous of different complications may burden others.

These symptoms may be related to your age and the underlying cause of low testosterone, but they can also be attributed to just how low your levels are. Below is an overview of the symptoms associated with different testosterone thresholds measured in the blood.

Table_Testosterone_levels2

Borderline low testosterone deficiency (12-15 nmol/L)

  • Reduced sex drive and an increased occurrence of erectile dysfunction.

  • A decrease in muscle mass and strength, and a generally lower threshold of tolerance to exercise.

Mild testosterone deficiency (10-12 nmol/L)

  • Further reduction in libido and more frequent erectile dysfunction.

  • Increased body fat and more prone to obesity.

Moderate testosterone deficiency (8-10 nmol/L)

  • Mood fluctuations with an increased risk of depression and anxiety.

  • Difficulties sleeping, including more frequent awakenings and finding it more difficult to get to and stay asleep.

  • Brain fog and a lack of ability to concentrate or focus.

  • Further weight increases and heightened risk of developing type 2 diabetes.

  • Lower bone mineral density, which increases the risk of osteoporosis and fractures.

Severe testosterone deficiency (<8 nmol/L)

  • Significant decrease in libido, frequent erectile dysfunction, and risk of infertility.

  • Hot flushes.

  • Increased risk of lower urinary tract symptoms, particularly in those with type 2 diabetes.

  • Increased risk of arterial hypertension (higher blood pressure), especially in those who smoke and/or are obese.

  • More pronounced mood swings with severe depression and emotional instability.

Zitzmann, M., Faber, S., & Nieschlag, E. (2006). Association of specific symptoms and metabolic risks with serum testosterone in older men. The Journal of Clinical Endocrinology and Metabolism, 91(11), 4335–4343. doi:10.1210/jc.2006-0401

Shigehara, K., Izumi, K., Kadono, Y., & Mizokami, A. (2021). Testosterone and bone health in men: A narrative review. Journal of Clinical Medicine, 10(3), 530. doi:10.3390/jcm10030530

Who’s at risk?

As well as age, testosterone deficiency (TD) is also more common among men with obesity, type 2 diabetes, or cardiovascular disease. Even without these conditions, it can affect men from a surprisingly young age.

If you have TD, you may be showing symptoms such as fatigue, low libido, loss of muscle mass, and depression. Although these symptoms alone don’t mean you have it, experiencing even one of them could point to something deeper.

Significant contributors to low testosterone

Age

Testosterone levels decline as men age, typically by 1% per year after the age of 30, primarily as a result of gradual reduction in testicular function.

Obesity

Excess body fat boosts the enzyme aromatase, which turns testosterone into oestrogen. This lowers testosterone levels and disrupts overall hormone balance.

Sleep irregularity

Testosterone production follows the circadian rhythm. Disrupted sleep patterns can interfere with this natural cycle, leading to decreased testosterone production over time.

Diabetes

Type 2 diabetes is characterised by insulin resistance, which can disrupt hormone signalling pathways, including those involved in testosterone production.

Cardiovascular disease

Men with cardiovascular disease may suffer from low testosterone due to impaired blood flow to the testes.

Diagnosing low testosterone

At Numan, we take a comprehensive diagnostic approach that integrates biological, psychological, and social factors. We conduct blood tests to understand your biology and use online and video consultations to learn more about your symptoms, overall health, and lifestyle. By combining these elements, we build a complete picture of your condition, enabling us to provide the most appropriate treatments for you.

3 step DIAGNOSIS

How it works

Whether you have low testosterone or not, our experts are dedicated to supporting you in understanding your symptoms and finding a treatment solution tailored to your needs.

Book your test

Do the AMS questionnaire 

Take 2 minutes to complete the online Ageing Males’ Symptoms (AMS) questionnaire, where you’ll be asked a few simple questions to assess your symptoms and their severity. 
Testosterone venous blood test

Take the Testosterone Venous Blood Test 

Book an appointment for a nurse visit or in-clinic test. This comprehensive test will accurately measure your testosterone levels, detect any underlying causes, and guide which treatments will be best for you.

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Have your free follow-up doctor consultation

Before the consultation, you’ll complete a health & lifestyle assessment covering topics such as diet, exercise, and medical history. Our doctor will conduct a thorough review and recommend the best treatment options for you.
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What can I do about low testosterone?
Managing low testosterone levels typically involves a combination of lifestyle changes and, in some cases, medical treatments. Here are some steps you can take.
Testosterone treatment

Managing low testosterone levels often involves medical interventions tailored to individual needs:

Testosterone treatment

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FAQS

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Knowledge

Testosterone: what you need to know

Reclaim Your Vitality

Experiencing decreased libido, fatigue, or increased body fat? You might have low testosterone. Check if low-T is affecting you today.

Test your Testosterone