LAST LONGER IN BED

Dapoxetine

Takes effect in: 1-2 hours

Lasts up to: 6 hours

Hassan

All content on this page has been medically reviewed by: Hassan Thwaini, Clinical Pharmacist and Copywriter, Master of Pharmacy (MPharm) on 30 March, 2026. GPhC Registration: 2221320View profile

Longer lasting sex

Dapoxetine is a tablet used to treat premature ejaculation, which you take before having sex. It’s clinically proven to give you more control over when you ejaculate.

How it works

Dapoxetine: the science

Increases serotonin

Dapoxetine is a selective serotonin reuptake inhibitor (SSRI), which increases serotonin levels in the brain.

Affects ejaculation

Increased serotonin activity helps delay ejaculation as the neurotransmitter plays a key role in the ejaculation process.

Extends duration

Typically taken 1-3 hours before sexual activity, Dapoxetine can significantly extend the duration of intercourse.

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FAQS

Your questions answered

Dapoxetine is a type of medicine known as an SSRI (selective serotonin reuptake inhibitor).

Dapoxetine’s job is to increase the activity of serotonin in the nervous system. Serotonin is a neurotransmitter that is involved in passing messages between nerve cells. One of its functions is to send the nerve messages that cause ejaculation.

By increasing the activity of serotonin in the nervous system, dapoxetine helps you to last longer during sex and gives you better control over when you ejaculate.

Dapoxetine can give you more control over when you ejaculate and allow you to last up to three times longer during sex. You should take one tablet, with a large glass of water, one to two hours before you plan on having sex.

Priligy is clinically proven to help men who are diagnosed with premature ejaculation last up to three times longer during sex.

Dapoxetine should be taken no more than once a day, and only before you plan on having sex. It’s a good idea to alternate between using dapoxetine during sex and having sex without using any medication.

This way you will be able to see if you can achieve better control over when you ejaculate without dapoxetine's help. Eventually, you should be able to achieve the same level of control both with and without the treatment.

Like most medicines, dapoxetine can cause potential side effects, although not everyone gets them. Common side effects include:

Headaches; dizziness; feeling ill; anxiety; asthenia; impaired concentration; constipation; diarrhoea; drowsiness; dry mouth; gastrointestinal discomfort; gastrointestinal disorders; hypotension; mood alteration; nausea; paraesthesia; sexual dysfunction; sinus congestion; sleep disorders; sweat changes; syncope; tinnitus; tremors; vasodilation; blurred vision; vomiting; yawning.

In order to minimise the risk of any side effects, stay well hydrated before taking dapoxetine.

A complete list of side effects you could potentially experience when taking dapoxetine can be found in the Patient Information Leaflet enclosed in your medication. Please make sure to read this in full before taking your treatment for the first time.

Dapoxetine is not suitable for those who have a history of depression, mania, syncope, bipolar disorder, postural hypotension, significant cardiac disease, or uncontrolled epilepsy. Further information about those who should not take dapoxetine can be found in the Patient Information Leaflet.

This depends greatly on your personal experience with PE. However, you should experience a noticeable increase in the time it takes to ejaculate.

For example, one study showed that men using dapoxetine (60mg) were able to last up to three times longer during sex than without it.

If dapoxetine doesn’t help you with premature ejaculation, there are a number of other things you can try:

Take a free online consultation with us and try another premature ejaculation treatment (such as Delay Wipes).

Speak to a psychotherapist to understand and overcome the psychological reasons behind premature ejaculation.

Practise certain behavioural techniques that can help to train your body to have more control over when you orgasm. The “squeeze” and “start-stop” techniques are two different strategies that can be practised during masturbation or sexual activity which, over time, can help to improve control over the timing of ejaculation.

We recommend getting in touch with one of our regulated clinicians to talk through your options and decide which steps are best for you. They are also able to recommend and prescribe treatments to help you find one that is suitable for your needs.

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