Health coaching
Patients who engaged with Numan’s coaching and mobile app lost, on average, an associated 50 % more weight than those taking medication alone over a 90 day period.*
What is Mounjaro?
Mounjaro (tirzepatide) is a new medication licensed for weight loss in certain groups of people. The active ingredient (tirzepatide) was originally designed for use in the treatment of type 2 diabetes,¹ used to help manage blood sugar levels more effectively, but due to positive impact on peoples weight being seen it was approved for use in the treatment of obesity in 2023. Taken once a week through a simple injection, Mounjaro is now licensed for use as a weight loss medication.¹
How effective is Mounjaro?
Mounjaro has shown great results for weight loss. Clinical studies have shown that people using Mounjaro lose more weight compared to those on other weight loss medications.
Patients lost an average of 9.81 kg (about 21.6 lbs) compared to placebo, with even higher reductions at higher doses.²
Weight loss increased with higher doses (5 mg, 10 mg, and 15 mg) demonstrating a clear dose-response relationship.²
More participants achieved at least 5%, 10%, and 15% body weight reductions compared to those on placebo or other diabetes medications.²
How does Mounjaro work?
Mounjaro has a unique approach to weight loss, as it targets two key pathways in the body. Here’s how it works:¹
Reduces appetite: Mounjaro helps to control hunger by affecting hormones that signal fullness, so you feel satisfied with less food.
Boosts insulin sensitivity: It improves how your body uses insulin, which helps keep blood sugar levels stable and prevents energy crashes.
Increases adiponectin levels: This hormone plays a role in regulating glucose levels and breaking down fatty acids, further supporting weight loss.
Long-lasting effects: With a half-life of five days, Mounjaro stays active in your system, allowing for convenient once-weekly injections.
Proven Results: Clinical studies have shown weight reductions of 16.5% to 22.4% over 72 weeks, even in patients without diabetes.
Why choose Numan for Mounjaro?
Numan isn't just an online pharmacy. We’re a holistic health provider offering complete care to help you get the most from your treatment. When you choose Mounjaro with Numan, you’ll also get access to:
Mounjaro treatment dosages
When starting Mounjaro, the dosage is gradually increased through a process called dose titration. This step-by-step approach allows your body to adjust to the medication smoothly and helps to minimise any potential side effects.²
It’s worth noting that not everyone will need the highest dose to see effective results. Your maintenance dose will depend on how your body responds throughout the treatment.²
| Dose | Use |
|---|---|
| 2.5mg | Injected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response. |
| 5.mg | Injected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response. |
| 7.5mg | Injected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response. |
| 10mg | Injected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response. |
| 12.5mg | Injected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response. |
| 15mg | Injected into the upper (subcutaneous) layer of the skin once a week. Dose is then titrated based on individual response. |
Mounjaro doses
2.5mg
Starting dose
5mg
Second dose, often prescribed after 4 weeks
7.5-15mg
Possible maintenance doses, titrated in 4 week increments
Who is eligible for Moujnjaro?
Mounjaro is recommended for managing obesity as part of a comprehensive plan that includes a reduced-calorie diet and increased physical activity. To be eligible for Mounjaro, you must meet the following criteria:3
An initial BMI of at least 30 kg/m².
Or a BMI of 27 kg/m2 to <30 kg/m2 (overweight) in the presence of at least one weight-related comorbid condition.
Mounjaro is designed to support significant weight loss alongside lifestyle changes, helping to improve health outcomes for those at higher risk due to obesity. If you fit these criteria, then you may be eligible for treatment.
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How to use Mounjaro
Taking Mounjaro is simple and straightforward. It comes in a pre-filled injection pen that you take once a week. You can inject Mounjaro in the following areas:
Stomach: At least 2 inches away from your belly button.
Thighs: Either thigh is suitable, just avoid the inner thigh.
Upper arm: The back of the upper arm if someone else is administering the injection.
Make sure to rotate the injection site each week to prevent irritation. Avoid areas that are bruised, red, or sore. After use, simply dispose of the pen safely in a yellow sharps bin and you’re good to go.
Important things to consider about Mounjaro
Keep your Mounjaro KwikPen in the refrigerator at 2°C to 8°C. Do not freeze it. If needed, Mounjaro can be stored unrefrigerated for up to 30 days, as long as the temperature stays below 30°C. After 30 days out of the fridge, the pen must be discarded, even if it hasn’t been used. Always check the expiry date before use. The shelf life of a refrigerated, unopened pen is 24 months, and the expiry date of your pen will be printed on the box.
While Mounjaro is generally well-tolerated, some people may experience side effects, primarily gastrointestinal, such as nausea, diarrhoea, and vomiting (may affect up to 1 in 10 people), especially during the initial phase of treatment. These side effects are usually mild to moderate and tend to decrease over time. It's important to read the Patient Information Leaflet provided with your package and consult your healthcare provider for a comprehensive list of side effects and advice on managing them.
For more information, please visit this page.
The duration of Mounjaro treatment depends on individual health goals and response to the medication. Implementing lifestyle changes alongside the treatment is crucial for sustained weight management. By building healthier habits you should be able to sustain your weight beyond taking the medication. Your healthcare provider will guide you on the appropriate duration based on your progress and overall health.
The difference between Mounjaro and Wegovy
It can be difficult to choose the right weight loss medication. However, a consultation with a Numan clinician can help you make a more informed decision. Below is a short summary of what the main differences are between Mounjaro and Wegovy.4,5
| Mounjaro | Wegovy | |
|---|---|---|
| Achievable weight loss, according to research | Up to 22.5% | Up to 18% |
| Protects against heart disease | No | Yes |
| Dosage | One weekly injection | One weekly injection |
Meet the experts
At Numan, our Weight Loss Programme is crafted by a team of dedicated experts in the fields of obesity management, behavioural change, and metabolic health.
With treatments like Mounjaro, which combines GLP-1 and GIP receptor agonists to suppress appetite and improve blood sugar regulation, our experts have designed a holistic programme that pairs advanced medications with personalised health guidance for maximum impact.
From nutritionists to behavioural psychologists, each expert brings a unique perspective to enhance your journey and help you lose weight effectively and sustainably.
Dr Luke Pratsides
Head of Medical
MBBS MSc MRCGP MFCI
Jess Uffindell
Registered Nutritionist
BANT CNHC BSc (Hons)
Mo Dekmak
Clinician
MPHARM PGDIP IPRESC
Shivani Sharma-Savani
Prescribing Lead
MPharm PGCert PCert IP
Faye Townsend
Senior Health Coach
AfN BSc BDA PGDIP BPS
OTHER SOLUTIONS
Effective treatments for weight loss
Proven solutions to change your weight, mindset, and behaviour.
Personalised health coaching
Health coaching is the backbone of lasting change in our programme. Alongside Mounjaro, our health coaches are here to support you in building sustainable habits in nutrition, exercise, sleep, and mindset.
While Mounjaro suppresses hunger and reduces food cravings, our coaches help you optimise these effects by guiding you toward a balanced lifestyle. From tips on satisfying, nutritious meals, to creative ways to integrate movement into your day, our coaches are committed to helping you unlock the full potential of your treatment.
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Obesity: fighting the disease with effective treatment
At Numan, we treat obesity not simply as a symptom but as a complex, chronic disease influenced by factors like genetics, hormones, and environment.6 Our approach recognises that effective treatment requires more than lifestyle changes alone - it demands a targeted medical response.
Mounjaro plays a critical role in this treatment plan by helping to reduce appetite and regulate blood sugar levels, making it easier to maintain a balanced diet and achieve weight loss goals. By addressing obesity as a disease, we’re able to support you with an evidence-backed, compassionate approach that integrates effective treatment, expert support, and personalised coaching.
I feel I can live a longer, happier life with less risk of cardiovascular issues. I've struggled with being overweight for many years, so the impact has been life-changing.
I discovered an old bag of clothes and couldn’t believe how many of them fit me where I would have had no chance before. I feel amazing. I think I look much better than I ever did.
I want to be in good shape to enjoy life. But be happy as I’m doing it, rather than miserable. And I think I’ve managed that with the programme.
FAQS
Your questions answered
Medically reviewed by Hassan Thwaini
Clinical Pharmacist and Copywriter, Master of Pharmacy (MPharm)
Knowledge
Weight loss: what you need to know
References
*Based on a retrospective study in 2,366 patients treated with a weightloss programme including a dual GLP-1 and GIP receptor agonist and a digital behavioural programme. Results seen after 3 months of treatment. Uplift attributed to the digital behavioural programme in patients with no prior use of weight loss medication. Individual results may vary based on lifestyle, usage of the app, and interactions with behavioural coaching.
1 Farzam K, Patel P. Tirzepatide. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025.
2 Lin F, Yu B, Ling B, Lv G, Shang H, Zhao X, et al. Weight loss efficiency and safety of tirzepatide: A Systematic review. PloS one. 2023;18(5): e0285197.
3 Tirzepatide for managing overweight and obesity. Nice.org.uk. https://www.nice.org.uk/guidance/ta1026/documents/draft-guidance-2 [Accessed 15th May 2025].
4 Garvey WT, Batterham RL, Bhatta M, Buscemi S, Christensen LN, Frias JP, et al. Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial. Nature medicine. 2022;28(10): 2083–2091.
5 Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, et al. Tirzepatide once weekly for the treatment of obesity. The New England journal of medicine. 2022;387(3): 205–216.
6 Lee A, Cardel M, Donahoo WT. Social and Environmental Factors Influencing Obesity. [Updated 2019 Oct 12]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK278977/
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